Sara Stokes Patterson

Postdoctoral Fellow at the University of Rochester

I am a postdoc studying foveal ganglion cell function with adaptive optics and calcium imaging in the lab of Dr. David Williams at the University of Rochester.

I recently completed a Ph.D. in Neuroscience in the Neitz lab at the University of Washington in Seattle. I studied color-coding retinal circuits in the primate retina. My research combined 3D reconstructions of retinal neurons from serial electron microscopy with single cell electrophysiology, computational models and human psychophysics.

Before graduate school, I spent a year as a post-bac at the NIH studying zebrafish cone photoreceptor development in the lab of Dr. Ralph Nelson. I graduated from Dickinson College with a B.S. in Neuroscience.

My full CV can be found here.

Publications

Bordt, A.S., Patterson, S.S., Kuchenbecker, J.A., Mazzaferri, M.A., Yearick, J.N., Ogilvie, J.M., Neitz, J., Marshak, D.W. (2022) Synaptic inputs to displaced intrinsically-photosensitive retinal ganglion cells in macaque retina. Scientific Reports, 12, 15160

Patterson, S.S., Bembry, B.N., Mazzaferri, M.A., Neitz, M., Rieke, F., Soetejdo, R., Neitz, J. (2022) Conserved circuits for direction selectivity in the primate retina. Current Biology

Patterson, S.S., Neitz, M., Neitz, J. (2021) S-cone circuits in the primate retina for non-image-forming vision. Seminars in Cell & Developmental Biology, In Press

Bordt, A.S., Patterson, S.S., Girresch, R.J., Perez, D., Tseng, L., Anderson, J.R., Mazzaferri, M.A., Kuchenbecker, J.A., Gonzales-Rojas, R., Roland, A., Tang, C., Puller, C., Chuang, A.Z., Ogilvie, J.M., Neitz, J., Marshak, D.W. (2021) Synaptic inputs to broad thorny ganglion cells in macaque retina. Journal of Comparative Neurology, 529(11), 3098-3111

Patterson, S.S., Mazzaferri, M.A., Bordt, A.S., Chang, J., Neitz, M., Neitz, J. (2020) Another Blue-ON ganglion cell in the primate retina. Current Biology, 30(23), 1409-1410

Patterson, S.S., Kuchenbecker, J.A., Anderson, J.R., Neitz, M., Neitz, J. (2020) A color vision circuit for non-image-forming vision in the primate retina. Current Biology, 30(7), 1269-1274

Neitz, A., Jiang, X., Kuchenbecker, J.A., Domdei, N., Harmening, W., Yan, H., Yeonan-Kim, J., Patterson, S.S., Neitz, M., Neitz, J., Coates, D.R., Sabesan, R. (2020) The effect of cone spectral tomography on chromatic detection sensitivity. Journal of the Optical Society of America A, 37(4), A245-255

Patterson, S.S.*, Bordt, A.S.*, Girresch, R.J., Linehan, C.M., Bauss, J., Yeo, E., Perez, D., Tseng, L., Navuluri, S., Harris, N.B., Matthews, C., Anderson, J.R., Kuchenbecker, J.A., Manookin, M.B., Ogilvie, J.M., Neitz, J., Marshak, D.W. (2019) Wide-field amacrine cell inputs to ON parasol ganglion cells in the primate retina. Journal of Comparative Neurology, 528(9), 1588-1598. (* co-first author)

Patterson, S.S., Kuchenbecker, J.A., Anderson, J.R., Bordt, A.S., Marshak, D.W., Neitz, M., Neitz, J. (2019) An S-cone circuit for edge detection in the primate retina. Scientific Reports, 9, 11913

Patterson, S.S., Neitz, M., Neitz, J. (2019) Reconciling color vision models with midget ganglion cell receptive fields. Frontiers in Neuroscience, 13, 865

Neitz, M., Patterson, S.S., Neitz, J. (2019) Photopigment genes, cones and color update: Disrupting the splicing code causes a diverse array of vision disorders. Current Opinion in Behavioral Science, 30, 60-66

Nelson, R.F., Balraj, A., Suresh, T., Torvund, M., Patterson, S.S. (2019) Strain variations in opsin peaks in situ during zebrafish development. Visual Neuroscience, 36, E010

Bordt, A.S., Perez, D., Tseng, L., Liu, W.S., Neitz, J., Patterson, S.S., Famiglietti, E.V., Marshak, D.W. (2019) Synaptic inputs and connectivity of a sparsely branched ganglion cell in rabbit retina. Visual Neuroscience, 36, E004

Manookin, M.B., Patterson, S.S., Linehan, C.L. (2018) Neural mechanisms mediating motion sensitivity in parasol ganglion cells of the primate retina. Neuron, 97(6), 1327-1340

Preprints

Godat, T., Cottaris, N., Patterson, S.S., Kohout, K., Parkins, K., Yang, Q., Strazzeri, J.M., McGregor, J.E., Brainard, D.H., Merigan, W.H., Williams, D.R. (2022) In vivo physiology of foveal retinal ganglion cells in Macaca fascicularis. bioRxiv

Bordt, A.S., Patterson, S.S., Kuchenbecker, J.A., Mazzaferri, M.A., Yearick, J.N., Yang, E.R., Ogilvie, J.M., Neitz, J., Marshak, D.W. (2022) Synaptic inputs to displaced intrinsically photosensitive ganglion cells in macaque retina. Research Square

Patterson, S.S., Bembry, B.N., Mazzaferri, M.A., Neitz, M., Rieke, F., Soetejdo, R., Neitz, J. (2021) Conserved circuits for direction selectivity in the primate retina. bioRxiv

Patterson, S.S., Neitz, M., Neitz, J. (2019) The spectral sensitivity of the neurons mediating black and white. bioRxiv

Book Chapters

Neitz, M., Patterson, S. S., Neitz, J. (2020) The genetics of cone opsin based vision disorders. The Senses: A Comprehensive Reference, 2nd edition, Vol. 1, 493-507

Patents

Neitz, J., Neitz, M., Kuchenbecker, J.A., Patterson, S.S., Neitz, A. (2022) Lighting devices, systems, methods for stimulating circadian rhythms. 17/612,061

Software

Connectomics: 3D analysis and visualization toolbox for serial electron microscopy. (SBFSEM-tools)
Github repositories for publications using SBFSEM-tools:

Adaptive Optics Object model and framework for organizing experiment data, metadata and code (AOData)

Electrophysiology: Stimulus protocols and online analyses for Symphony and Stage (patterson-package).

Optical Coherence Tomography (OCT): Analysis and user interface for semi-automated segmentation of retinal layers and choroid (OCT-tools).

Links

Profiles: Github, Google Scholar, Research Gate, Orcid, Codepen, Twitter.
University of Rochester: Center for Visual Science, Institute of Optics, Advanced Retinal Imaging Alliance (ARIA).
University of Washington: Neitz lab, Neuroscience Graduate Program